카페인은 탈모를 촉진한다.

Research Summary & Abstract: PMID: 41187241. 해당 의학 논문의 요약문 및 학술 정보는 원본 링크를 참조해 주세요.

Research Summary & Abstract: PMID: 40986632. 해당 의학 논문의 요약문 및 학술 정보는 원본 링크를 참조해 주세요.

Research Summary & Abstract: Hair loss has been increasing in modern society due to various factors, leading to growing interest in scalp care and func tional ingredients. In particular, recent international studies have reported that caffeine, through the inhibition of phos phodiesterase (PDE), stimulates cellular metabolism and proliferation. Accordingly, a wide range of caffeine-containing products, such as shampoos and scalp ampoules, have been introduced in the domestic market. However, empirical studies examining the relationship between caffeine and scalp hair loss remain limited in Korea. This study aimed to investigate the effects of a caffeine-based scalp ampoule combined with Microneedle Therapy System (MTS) on scalp and hair conditions in women in their 40s. A within-subject controlled prospective design was employed, in which the left and right scalp of the same participants were assigned to the control and experimental groups, respectively. The study included 10 women in their 40s with hair loss, and treatments were administered once a week for four weeks. The experimental group received a caffeine-containing ampoule, while the control group received a caffeine-free ampoule. Evaluations were conducted at baseline, 2 weeks, and 4 weeks using an AI-based scalp diagnostic device. A total of 10 indicators were measured, including pore density, number of hairs per pore, hair thickness, and hair volume. Data were analyzed using paired t-tests and repeated measures ANOVA. The results showed that the experimental group demonstrated statistically significant improvements in hair structural in dicators, including pore density, number of hairs per pore, hair thickness, and hair volume (p < .05), compared to the con trol group. In addition, scalp temperature and sensitivity were significantly reduced, indicating stabilization of the scalp environment. However, no significant differences were observed in moisture level, sebum, and odor. These findings sug gest that the combined effects of enhanced transdermal delivery through MTS and the physiological action of caffeine contributed to improvements in scalp and hair conditions. Therefore, the combined use of a caffeine-based scalp ampoule and MTS may serve as an effective management ap proach for improving scalp environment and hair condition.